Streptococcus salivarius M18 (BLIS M18™) is a bacterial replacement probiotic speci cally derived from the oral cavity and designed for use in the oral cavity. + BLIS M18; has been shown to be effective at killing S. mutans, a leading causative agent of tooth decay, during laboratory based trials. Bacteria responsible for the initiation of dental caries often produce lactic acid from dietary carbohydrate. This degrades the tooth enamel and dentine which can lead to cavities and eventual tooth loss. + BLIS M18 has been shown to produce the enzyme urease which can release ammonia in saliva helping to neutralize the acid produced by the cariogenic bacteria. 30 Peppermint flavoured probiotic lozenges